According to the NYSDOT, the Bronx River Parkway carries approximately 100,000 vehicles per day in the South Bronx, approximately 75,000 vehicles per day in the northern Bronx, and approximately 60,000 vehicles per day through Westchester County. From April to October, a seven-mile stretch of the Bronx River Parkway from EXIT 4 (Scarsdale Road) in Tuckahoe north to EXIT 22 (County Center) in White Plains closes to automobile traffic each Sunday between 10 AM and 2 PM. During those times, the Westchester County Parks Department runs "Bicycle Sundays" along this stretch of the parkway. The "Bicycle Sunday" program, which has its roots in a one-day bicycle rally in 1974 to benefit the Muscular Dystrophy Association, was intended to demonstrate the need for the development of safe bicycling throughout Westchester County. By 1975, each Sunday from April to October was designated a Bicycle Sunday. Bicycle Sundays are one of the most popular Parks Department programs in Westchester county. Today, about 3,500 people participate in this event each week.

From Sound View Park north to the Bronx-Westchester border, the New York City Department of Transportation (NYCDOT) maintains the limited-access Bronx River Parkway, and the New York City Parks Department maintains surrounding rights-of-way. Along this section, major reconstruction work is undertaken by the New York State Department of Transportation (NYSDOT), which also installs signs and reference markers. From the Bronx-Westchester border north to Valhalla, the Westchester County Department of Public Works (WCDPW) maintains both the newer limited-access section and the original "hybrid" section.